Talc pleurodesis: Evidence of systemic Inflammatory response to small size talc particles
نویسندگان
چکیده
منابع مشابه
Evidence that mesothelial cells regulate the acute inflammatory response in talc pleurodesis.
Intrapleural instillation of talc is used to produce pleurodesis in cases of recurrent malignant pleural effusions. The mechanisms by which pleurodesis is produced remain unknown but may involve either injury or activation of the mesothelium. The aim of the current study was to assess the inflammatory response of pleural mesothelial cells to talc in an experimental model in rabbits. A group of ...
متن کاملSterilization of Talc for Pleurodesis *
Although talc has been used as a pleurodesis agent since 1935, a sterilization protocol has not been established. We obtained USP asbestos-free talc from six different suppliers and sterilized each using dry heat, gamma irradiation, and ethylene oxide gas. Aerobic, anaerobic, and fungal cultures were obtained prior to sterilization, and 1, 30, and 90 days after sterilization. Bacillus species w...
متن کاملInfluence of particle size on extrapleural talc dissemination after talc slurry pleurodesis.
BACKGROUND Cases of acute respiratory failure reported after talc pleurodesis have raised concerns about its safety. It has been speculated that this pulmonary inflammatory syndrome is secondary to the extrapleural dissemination of the talc particles. STUDY OBJECTIVES To test the hypothesis that particle size influences extrapleural talc deposition and pleural inflammation after talc slurry p...
متن کاملObservational analysis on inflammatory reaction to talc pleurodesis: Small and large animal model series review
Talc pleurodesis has been associated with pleuropulmonary damage, particularly long-term damage due to its inert nature. The present model series review aimed to assess the safety of this procedure by examining inflammatory stimulus, biocompatibility and tissue reaction following talc pleurodesis. Talc slurry was performed in rabbits: 200 mg/kg checked at postoperative day 14 (five models), 200...
متن کاملBilateral talc pleurodesis in metastatic pneumothorax.
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ژورنال
عنوان ژورنال: Respiratory Medicine
سال: 2009
ISSN: 0954-6111
DOI: 10.1016/j.rmed.2008.07.021